Gene: LAPTM4B

official authority: LAPTM4B, lysosomal protein transmembrane 4 beta

• Synonyms: LAPTM4beta; LC27
• Other Designations: lysosomal associated protein transmembrane 4 beta; lysosomal associated transmembrane protein 4 beta
• Description: lysosomal protein transmembrane 4 beta
• Type: protein-coding
• Chromosome: 8
• Organism: Homo sapiens
• Omim: 0
  
• title:Lysosomal protein transmembrane 4 beta;
• tissue expression: adrenal gland; ascites; bladder; blood; bone; bone marrow; brain; cervix; connective tissue; ear; embryonic tissue; esophagus; eye; heart; intestine; kidney; larynx; liver; lung; lymph node; mammary gland; mouth; muscle; nerve; ovary; pancreas; parathyroid; pharynx; pituitary gland; placenta; prostate; salivary gland; skin; spleen; stomach; testis; thymus; thyroid; umbilical cord; uterus; vascular; adrenal tumor; bladder carcinoma; breast (mammary gland) tumor; cervical tumor; chondrosarcoma; colorectal tumor; esophageal tumor; gastrointestinal tumor; germ cell tumor; glioma; head and neck tumor; kidney tumor; leukemia; liver tumor; lung tumor; lymphoma; non-neoplasia; normal; ovarian tumor; pancreatic tumor; primitive neuroectodermal tumor of the CNS; prostate cancer; retinoblastoma; skin tumor; soft tissue/muscle tissue tumor; uterine tumor; embryoid body; blastocyst; fetus; neonate; infant; juvenile; adult;

Molecular alterations reported in literature

Gene products

genomic	RNA	protein	Uniprot accession	PDB Structure
NC_000008.10	NM_018407.4	NP_060877.3	Q86VI4	---

Gene Expression Data

• genes highly correlated to LAPTM4B in a primary tumour dataset
• Differential Gene Expression
• Gene Expression Atlas

Interacting miRNA

• view miRNA list

Protein: LAP4B_HUMAN

• Description: AltName: Full=Lysosome-associated transmembrane protein 4-beta;
• Length: 370 aa
• Function:
• Location: Endomembrane system; Multi-pass membrane protein.

InterPro domains

• Lysosomal-associated transmembrane protein 4B (IPR018401)
• Golgi 4-transmembrane spanning transporter (IPR004687)

SNPs and Protein Structural Models

• view SNPs list and use modelling tool

Human Protein Atlas stained tissues

• Protein expression in breast cancer tissues
• show related stained tissue images

Pathways

• Lysosome (KEGG map) (KEGG ontology)

Gene Ontology

• Processes
  • transport (GO:0006810)
• Components
  • endomembrane system (GO:0012505)
  • membrane (GO:0016020)
  • integral to membrane (GO:0016021)

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Note: data printed here are integrated from public resources