ProCMD : 3D Protein C Mutations Database

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Protein C overview
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   Model your mutant

ermanna.rovida *



This server mutates a single residue in the PDB structure of Activated Protein C using the script "" of Modeller.
The script replaces the existing residue with the mutated residue, it optimizes the conformation of the mutant sidechain by conjugate gradient and refine it using some molecular dynamics.

Warning: the procedure is fully automatic and there is no check of the results. The users should carefully evaluate the results before using them.

Please insert the PDB number of the residue you want to mutate, the mutated amino acid and the chain :

  PDB number

  mutated amino acid (e.g. 'ASP' for aspartic acid)


now click to obtain your mutated pdb file