Project

PROMED-COG

Protein enriched Mediterranean diet and exercise to prevent undernutrition and promote healthy cognitive ageing
Application Areas
Research Areas
Research Lines
Staff
WEBSITE

ITB Principal Investigator

Name

Protein enriched Mediterranean diet and exercise to prevent undernutrition and promote healthy cognitive ageing

Acronym

PROMED-COG

Location

Segrate

Start Date

2021

End Date

2025

Funder

European Horizon 2020 Joint Programming Initiative “A Healthy Diet for a Healthy Life” and ERA-NET Cofund ERA-HDHL (GA N° 696295)

Partners

CNR (IN) University of Padova Queen’s University Belfast (UK) University College Dublin (Ireland) Wageningen University (The Netherlands) Friedrich-Alexander-Universität Erlangen-Nürnberg (Germany)

The PROMED-COG project aimed to integrate epidemiological and intervention research to generate new and critical insights into the role of undernutrition in neurocognitive ageing. It investigated how these effects vary according to sex, genetic risk, and the timing of undernutrition exposure, and how changes in dietary and physical activity behaviours may help reduce the burden of undernutrition and neurodegeneration. This work is of major public health relevance given Europe’s rapidly ageing population and the established link between undernutrition and dementia risk. The resulting scientific evidence will be translated into public health and clinical practice recommendations to prevent undernutrition and support healthy neurocognitive ageing among older European citizens.
  • Prinelli F, Noale M, Conti S, Ravelli A, Sergi G, Maggi S, Ceolin C, Brennan L, de Groot LC, McEvoy CT, Trevisan C; PROMED-COG Consortium. Socioeconomic status modifies the association between adherence to the Mediterranean diet and cognitive outcomes: results from the Collaborative PROMED-COG Pooled Cohorts Study. DOI 10.1007/s00127-025-02993-2
  • Ceolin C, Prinelli F, Trevisan C, Ravelli A, Conti S, Brennan L, de Groot LCPGM, McEvoy CT, Maggi S, Sergi G, Noale M; PROMED-COG Consortium. Body weight trajectories from midlife are associated with cognitive decline in advanced age. DOI 10.1038/s41598-025-08725-5
  • Prinelli F, Trevisan C, Conti S, Maggi S, Sergi G, Brennan L, de Groot LCPGM, Volkert D, McEvoy CT, Noale M; PROMED-COG Consortium. Harmonizing Dietary Exposure of Adult and Older Individuals: A Methodological Work of the Collaborative PROMED-COG Pooled Cohorts Study. DOI 10.3390/nu16223917
  • Noale M, Prinelli F, Conti S, Sergi G, Maggi S, Brennan L, de Groot LC, Volkert D, McEvoy CT, Trevisan C; PROMED-COG Consortium. Undernutrition, cognitive decline and dementia: The collaborative PROMED-COG pooled cohorts study. DOI 10.1016/j.clnu.2024.09.001
  • Ward NA, Reid-McCann R, Brennan L, Cardwell CR, de Groot C, Maggi S, McCaffrey N, McGuinness B, McKinley MC, Noale M, O’Neill RF, Prinelli F, Sergi G, Trevisan C, Volkert D, Woodside JV, McEvoy CT. Effects of PROtein enriched MEDiterranean Diet and EXercise on nutritional status and cognition in adults at risk of undernutrition and cognitive decline: the PROMED-EX Randomised Controlled Trial. DOI 10.1136/bmjopen-2022-070689
  • Townsend RF, Logan D, O’Neill RF, Prinelli F, Woodside JV, McEvoy CT. Whole Dietary Patterns, Cognitive Decline and Cognitive Disorders: A Systematic Review of Prospective and Intervention Studies. DOI: 10.3390/nu15020333
  • O’Neill RF, Brennan L, Prinelli F, Sergi G, Trevisan C, De Groot LCPGM, Volkert D, Maggi S, Noale M, Conti S, Adorni F, Woodside JV, McKinley MC, McGuinness B, Cardwell C, McEvoy CT. PROtein enriched MEDiterranean diet to combat undernutrition and promote healthy neuroCOGnitive ageing in older adults: The PROMED-COG consortium project. DOI: 10.1111/nbu.12571
  • Townsend RF, Logan D, O’Neill RF, Prinelli F, Woodside JV, McEvoy CT. Whole Dietary Patterns, Cognitive Decline and Cognitive Disorders: A Systematic Review of Prospective and Intervention Studies. DOI 10.3390/nu1502033