Project

AD-CAN

Genetic epidemiology study on the inverse association of occurrence between Alzheimer's disease and cancer
Application Areas
Research Areas
Research Lines
Staff
WEBSITE

ITB Principal Investigator

Name

Genetic epidemiology study on the inverse association of occurrence between Alzheimer's disease and cancer

Acronym

AD-CAN

Location

Segrate

Start Date

2017

End Date

ongoing

Funder

Internal funding

Partners

UniMI

Study of the inverse relationship in occurrence between neurodegenerative diseases and cancer: investigation of the effect of differences in the distribution of modifiable risk factors and genetic variants in patients affected by Alzheimer’s disease (AD) and/or cancer. The project aims to identify genetic variants associated with Alzheimer’s disease and different types of cancer that may underlie the inverse relationship in occurrence between the two diseases. The study analyses large datasets (DbGAP, UK Biobank) to identify genetic patterns associated with the lower-than-expected co-occurrence of the two diseases, by means of Genome Wide Association Study (GWAS) and ML methods.