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Personale
- Gaetano Ferraiuolo
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- Gianluca De Bellis
- Raffaello Viganò
- Federica Prinelli
- Francesca Brambilla
- Rossana Rossi
- Mauro Marzorati
- Davide Perico
- Silvia Conti
- Nithiya Jesuthasan
- Francesca Colombo
- Gaetano Stea
- Giuseppe Sabatelli
- Gianluca Cecinato
- Vito F. Licciulli
- Giuseppe Cananzi
- Andreas Gisel
- Domenico Catalano
- Guido Cauli
- Giorgia Miniello
- Nicola Losito
- Maria Liguori
- Rolland A. Reinbold
- Tommaso Selmi
- Paride Pelucchi
- Arianna Tisba
- Martina Scichilone
- Valentina Rosti
- Nicole Fratini
- Chiara Bellei
- Giorgio Grillo
- Arianna Consiglio
- Antonella De Palma
- Valeria Bellettato
- Francesco Fossari
- Cinzia Cocola
- Dario Di Silvestre
- Ugo M. Iannacchero
- Roberta Bordoni
- Tania Camboni
- Eva Maria Pinatel
- Alessandra M. Mezzelani
- Eleonora Mangano
- Ada Sula
- Ingrid Cifola
- Naomi Scarano
- Maria I. Curci
- Clarissa Consolandi
- Marco Severgnini
- Francesca Minnai
- Martina Esposito
- Pasqualina D’Ursi
- Ettore Mosca
- Chiara Lanzuolo
- Federica Chiappori
- Gabriele A. Trombetti
- Giorgia Maroni
- Elena Levantini
- Maddalena Di Nardo
- Claudia Bearzi
- Igea D’Agnano
- Laura Vilardo
- Fabio A. Zucca
- Eleonora Piscitelli
- Francesca A. Cupaioli
- Alessandro Orro
- Ivan Merelli
- Andrea Manconi
- Antonio Musio
- Aleksandra Sojic
- Fulvio Adorni
- Roberta Alfieri
- Domenica D’Elia
- Camilla Ceccarani
- Elisa Scalco
Progetti
- ML for complex diseases
- Spinal muscolar atrophy translating customized health innovations to newborn and grown-up patients – SMA-TCHING
- Bulbar onset ALS clustering by clinical informed multi-omics (BULB-OMICS)
- InvAt – Active and healthy aging
- Valutazione dell’efficacia di un programa nutrizionale e di attività fisica per migliorare la performance funzionale e prevenire l’obesità sarcopenica: lo studio pilota NUTRINVAT
- Organi di maiale per dare speranza a chi è in attesa di trapianto
- Emerging role of digenic or pseudo-digenic inheritance models in Mendelian diseases: implication of hypomorphic variants in Noonan syndromes pathogenetic mechanisms and in RAS pathway deregulation
- ELIXIR x NextGenerationIT: Consolidation of the Italian Infrastructure for Omics Data and Bioinformatics.
- DATAREX – Data Management for Research in ELIXIR
- NUTRAGE – “NUTRIZIONE ALIMENTAZIONE E INVECCHIAMENTO ATTIVO”
- Longitudinal transcriptomic impact of Risdiplam in adult Spinal Muscular Atrophy
- Laser induced breakdown spectroscopy On a STrip to monitor Alzheimer’s disease
- COMBATCOVID19
- Identification of miRNAs from grapevine (Vitis vinifera) with cross-kingdom bioactivity and development of a novel plant-based delivery system
- INnovazione, nuovi modelli TEcnologici e Reti per curare la SLA
- NORA: a sequencing-based approach to define NucleOid stRuctural Alterations in Helicobacter pylori dormancy.
- Nasal microbiota, bronchiolitis and air pollution: the Good, the Bad and the Ugly
- Effect of recombinant protein addition on sperm parameters of porcine and bovine sperm after thawing selected by comparative seminal plasma proteomics
- UNSOLVED CHALLENGES IN DYSTROGLYCANOPATHIES: THE SEARCH FOR NOVEL MOLECULAR PREDICTORS FOR αDG GLYCOSYLATION DIAGNOSIS AND MANAGEMENT
- Alignment of the Interoperability Platform FAIR Service Architecture Framework with the Data Platform, Communities, and ELIXIR Projects
- Identification of new therapeutic targets in rare neurodegenerative diseases: the role of circulating extracellular vesicles
- Un approccio multidisciplinare per la ricerca di biomarcatori molecolari orientati alla valutazione del profilo rischio/beneficio nel trattamento dell’Atrofia Muscolare Spinale.
- BEST-FU study: 20-year observational study on health determinants
- EPICOVID19: Indagine Epidemiologica Nazionale COVID-19
- NUTRAGE – The role of lifestyle in promoting active ageing and understanding the underlying biological mechanisms
- INCT Reprodução Animal 2022
- Comparison, benchmarking and dissemination of proteomics data analysis pipelines
- SIGNALING THE ORGANELLE UNFOLDED PROTEIN RESPONSE
- AD-CAN Genetic epidemiology study on the inverse association of occurrence between Alzheimer’s disease and cancer
- ALIFUN – Sviluppo di alimenti funzionali per l’innovazione dei prodotti alimentari di tradizione italiana
- CNR.BiOmics: Centro nazionale di ricerca bioinformatica per le scienze “omiche”
- PRR.AP026/IR_Research Infrastructures PRR.AP026.013.006/ITB MILANO -ELIXIR x NextGenerationIT: Consolidation of the Italian Infrastructure for Omics Data and Bioinformatics
- Relation between SARS-CoV2/Respiratory microbiome in adenoid tissue in pediatric age
- CN_National Biodiversity Future Center – NBFC
- Identification of molecular mechanisms leading to activation of pathogenic Th1/17 cells by pathobionts and gut microbiota in Crohn’s disease: a new target for therapeutic strategies.
- Identification and functional modulation of bacterial and human RNA-targets to prevent generation of pathogenic intestinal Th17cells: perspective for a novel RNA-based therapy in Crohn’s disease” –
- COMCAT: Causes of death in a cohort of intravenous drug users recruited in Milan between 1980 and 1988. Temporal trend analysis of AIDS mortality
- A randomized pilot study on the impact of a modified Mediterranean diet (DMM) on the intestinal microbiota and clinical outcome in patients with colorectal cancer undergoing active medical oncology treatment.
- PNRM
- Investigating the impact of the lamina-associated TDark network on chromatin architecture dysfunction in Emery-Dreifuss Muscular Dystrophy
- Analysis of genome function recovery upon pharmacological treatment in Hutchinson-Gilford Progeria Syndrome
- Multifocal dynamic bioengineered 3D cardiac models to unveil the epigenetic remodelling of SARS-CoV-2 infection
- Dissecting the chromatin condensates underlying the maintenance of human T cell quiescence
- Multiomics pRofiling of patient spEcific Models to predict druggable targets in severe neuromuscular rare diseases
- Targeting B cell-mediated autoimmunity in patients with thymic epithelial tumors
- Deciphering and Targeting VEXAS
- A Multifactorial Intervention for Successful Aging
- Unraveling molecular targets of myeloid-driven inflammation in VEXAS syndrome
- OT-HD: does oxytocinergic neuromodulation of striatal network have a role in the pathophysiology of Huntington’s Disease?
- Improving the safety and long-term efficacy of hematopoietic stem cell-based Gene Therapy and optimization of the treatment protocol through in vivo characterization of the stem cell proliferation stress during the hematopoietic reconstitution.
- ImmuNE-MOdulation mechanisms in myelofibrosis
- National Centre for HPC, Big Data and Quantum Computing Spoke 8: In-Silico Medicine & Omics Data
- Study of the molecular determinants of psychocognitive profile in children and adolescents affected by Noonan Syndrome
- NUTRAGE – Research on biomarkers for the clinical monitoring of aging‑related diseases and drug response.
- MATITE – a Multi-omic Approach To Investigate The human repeatomE
- Normalizing the fibrotic tumor microenvironment to reactivate immune response in pancreatic ductal adenocarcinoma: the RNASET2 alarmin-like molecule as novel immunomodulatory effector for (combination) therapies
- Cerebral organoids: implementation of an innovative 3d model to study human brain neurodevelopment and neurological diseases
- Analysis of neuromelanins and metals involved in neurodegeneration of Parkinson’s disease using novel high resolution SIMS methods
- Parkin Protects Against Dopamine-Induced Neurotoxicity
- Small extracellular vesicles as liquid biomarkers for non-invasive monitoring of malignant glioma
- Role of the extracellular matrix in the regulation of cardiac sympathetic innervation in Duchenne muscular dystrophy
- Exploring the genetic and epigenetic background underlying phenotype’s variability in Emery Dreifuss Muscular Dystrophy
- Human 3D myocardium-integrated competent coronary vessel to unveil epigenetic dynamics of SARS-CoV-2 infection on heart
- An integrated approach to predict disease activity in the early phases of Multiple Sclerosis
- Integration of clinical and multi-omics multiple sclerosis data into a predictive algorithm of disease activity to accelerate personalized medicine
- Chondroitin sulfate proteoglycan‐4, secreted by a binding imbalance between SP1 and NF‐kB on CHST11 gene, triggers sympathetic cardiac denervation in Duchenne Muscular Dystrophy
- Dissecting the role of heterochromatic conformation in age-related sarcopenia and frailty
- Generation of patient-specific human tissues for testing the efficacy of new drugs
- Generation of patient-specific tissues for the repair of damaged organs
- NUTRAGE – Ruolo delle proteine TMEM nel NOTCH signaling
- Heparanase inhibition as a multifunctional targeting approach in cancer
- Sviluppo di una innovativa piattaforma di screening per il design di CRISPR ad elevate efficacia e specificità
- The Global Grant for Gut Health
- Integrated PET/MRI and germline variants to differentiate brain tumor recurrence from iatrogenic changes in children
- Pilot pharmacogenomic study of the smoking cessation therapies
- Complex interactions between genetic variants and lung tissue transcription in the outcome of lung adenocarcinoma
- Pharmacogenomics of opioids for cancer pain: a path to personalized medicine
- Multi-omics approach for the identification of non-invasive biomarkers of host and tumor response to immune checkpoint inhibitors in advanced lung cancer patients
- Host genetics and pathogenetic mechanisms of COVID-19
- Integrating pharmacogenomic and pharmacometabolomic data towards personalized opioid therapies for cancer pain
- A `System Epidemiology’ Approach to Explore the Complex Relationship between Nutrition and Brain Aging
- PRIN 2022, Role of aquaporin-4 isoforms in brain edema
- Role of SMC1A in ntellectual disability and pharmaco-resistant epilepsy
- Cell-free” MEsenchymal Regenerative therapy for aLpha-1-antitrypsIN deficiency-associated lung diseases
- Non-canonical roles of cohesin and Separase, beyond that of cohesion
- MesenchymAl stem cell fReeze-dried secreTome for lUng fibROsis therapy: efficacy proof-of-concept in a murine model
- PROMED-COG Protein enriched Mediterranean diet and exercise to prevent undernutrition and promote healthy cognitive ageing
- REte di Genomica Integrata per Nuove Applicazioni in medicina di precisione
- Genome, Environment, Microbiome & Metabolome in Autism: an integrated multi-omic systems biology approach to identify biomarkers for personalized treatment and primary prevention of Autism Spectrum Disorder
- IDENTITA’: Rete Integrata meDiterranea per l’osservazione ed Elaborazione di percorsi di Nutrizione personalizzaTa contro la malnuTrizione
- SARS-CoV-2-induced endothelial cell dysfunction: mechanisms and therapeutic approaches
- Role of Ribosomal protein L8 gene amplification in ovarian cancer
- Structural and functional characterization of the essential transcriptional regulator HP1043 of Helicobacter pylori as target for new antibacterial drugs
- Development of Deep-Learning models robust to MRI alterations – application to kidney segmentation
- Sviluppo e ottimizzazione di metodi di machine-learning per la costruzione di modelli predittivi radiomici da immagini oncologiche
- The Italian Network of Biobanks and BioMolecular Resources
- Strengthening Biobanking and Biomolecular Resources Research Infrastructure of Italy
- High-resolution study of translational dynamics in human epithelial stem cells
- Deciphering the whole-brain circuit mediating traumatic memory attenuation
- Bioelectronic Modulation of Tumor Innervation to Inhibit Tumor Growth: A Proof of Concept
- Exploring BMI1’s Role in Osimertinib Resistance and EGFR Mutation-Specific Metabolic Reprogramming in NSCLC
- Epitranscriptomic Landscape and Onco-transcriptomic/Proteomic Signature in Cancer Patients for Better Classification and Therapeutic Approaches
- AI-based methods to improve stratification of patients affected by Polycystic Kidney Disease using multi-parametric MRI
- Improving therapy response in EGFR mutant lung cancer by targeting transcriptional alterations in tumor and immune cells
- Big Data Analytics Pipeline for the Identification of Heterogeneous Extracellular non-coding RNAs as Disease Biomarkers
- Harmonising standardisation strategies to increase efficiency and competitiveness of European life-science research (CA15110)
- Statistical and machine learning techniques in human microbiome studies (CA18131)
- Ge.Co.Sa. – Gestire le Comorbidità legate alla Sarcopenia
- Tuscany Health Ecosystem