A pan-European Biobanking Research Infrastructure, building on existing infrastructures, resources and technologies, specifically complemented with innovative components and properly embedded into European ethical, legal and societal frameworks. BBMRI will contribute to increase the scientific excellence and efficacy of European research in the biomedical sciences as well as expand and secure competitiveness of European research and industry in a global context.
The BioinfoGRID Specific Support Action (SSA) will combine Bioinformatics services and applications for molecular biology users with the Grid Infrastructure created by the EGEE Project (6th Framework Program). BioinfoGRID will evaluate genomics, transcriptomics, proteomics and molecular dynamics applications studies based on GRID technology. The BioinfoGRID SSA will establish a common ground for collaboration between the European Grid Infrastructure providers and the Bioinformatics research user community in various fields of Bioinformatics applications (Biology, Computational Chemistry, Medicine and Biotechnology). This will be achieved through specific studies for each reference application in the Bioinformatics domain in which experts of various disciplines can collaborate on the solution of highly complex problems.
Biodiversity Virtual e-Laboratory (BioVeL) is a project proposal in response to the European Commission's FP7 2011 Call "INFRA-2011-1.2.1 — e-Science environments".
BioVeL meets the needs of Europe's Biodiversity Science research community with tools for pipelining data and analysis into efficient workflows, urgently needed to understand biodiversity in a rapidly changing environment.
The CNR-Bioinformatics project is made up of researchers from various CNR departments, in order to achieve specific research in the field of Bioinformatics.Recent results from sequencing projects of the genome of different species have laid the foundations for the study of modern industrial applications derived from genomics and proteomics. In this contest, the CNR-Bioinformatics project will support research in public health, in Universities, in public sector research and industries, for the development of new strategies for the analysis of genetic data in the biomedical and biotechnological fields. The aim of the Bioinformatics project is to establish a network of specific skills within CNR departments able to adequately respond to bioinformatics needs generated by CNR's projects and to constitute a pool of expertise to better participate in national and international projects. This project will support the development of new approaches to analysis and management of genomic and proteomic data in biomedical, biotechnological, agro-industrial molecular design fields. This project aims to conduct coordinated research activities, aid technological transfer and to run training programmes, all of which will contribute to the development of new and advanced bioinformatics tools that will be made available to the entire national and international scientific community. In particular, activities will be carried out to develop new bioinformatics methodologies that will find immediate application in projects of national interest in the emerging areas of System Biology, in the study of complex systems, of information technology and Grid computing applied to biology and medicine.
The advent of the sequencing era has opened new frontiers for plant genomics. Several organisms have been already sequenced and others, including important crop plants, are underway. In this context the Italian Ministry of Agriculture (MiPAAF) sponsored the national project "DRUPOMICS" with the aim of joining the International initiative, leaded by US Institutions, in the sequencing of the peach genome. Fourteen scientific Italian Institutions collaborate to this project.
The targets of the project are user communities that require large computing power not available or accessible in current scientific e-Infrastructures. In order to support the specific needs of these scientific and other communities The consortium will interconnect the largest European Service Grid infrastructure (EGEE) with existing Desktop Grid (DG) systems in a strong partnership with the EGEE consortium. Service Grids (SG) are more flexible and can accommodate a broader variety of applications than Desktop Grids, however, their setup and maintenance require more efforts, highly skilled IT specialist, and dedicated resources. On the other hand, Desktop Grids are currently restricted solely to a subclass of compute-intensive applications but these easy-to-scale systems are able to collect 1-2 orders of magnitude more compute power by utilizing the involved spare and volunteer IT resources at a fraction of the cost.
The goal of this project is to analyze the role of C/EBP in pulmonary stem cell differentiation. Furthermore we are interested in defining the role of C/EBP in experimental models of lungs cancer and tobacco-damaged epithelium.
Studio multidisciplinare finalizzato all'identificazione e caratterizzazione di marker innovativi in grado di definire il ruolo di virus epatotropi nello sviluppo del carcinoma epatocellulare: un modello di incontro tra ricerca di base ed applicativa.
The project will develop expertise for the whole supply chain of "omic" sciences, with particular focus on genomics, proteomics, bioinformatics and systems biology.
Italian network for the biomulecolar data analysis and intercation related to genomics, transcriptomics, proteomics and systems biology.
Recent progresses in the biomedical field have made compulsory the organization of platforms capable of offering a reasonable support for research in life sciences. Our aim is to organize an Interdisciplinary Laboratory of Bioinformatics Technologies (LITBIO), applied to Genomics and Proteomics. This infrastructure will be capable of challenging international research and development programmes for the development of new analysis strategies of biomedical and biotechnological data. The project's aim is to establish a realistic cooperation between private and public structures and to stimulate the growth of new enterprises in the sector of Bioinformatics. Evaluation of an investment fund for creating a start-up during the first three years of the project. This platform will help the interdisciplinary formation of new job profiles in bioinformatics, biotechnologies and medicine.
NanoTOES has 6 major scientific objectives, which are indicated in the following list.
Identify mechanisms by which nanomaterials induce cellular stress and immune activation;
Correlate size, shape, composition, coating of nanomaterials with defined cellular responses;
Distinguish cell-specific from general cellular responses for cells from selected tissues ;
Identify the relevance of bystander substances and contaminants for nanotoxicity;
Analyse the influence of biological compounds and entities on engineered NP;
Develop and modify laboratory methods to allow their application in the work-place and in the environment;
The aim of the Net2Drug project is to develop a toolbox that combines different experimental high-throughput methods within a bio- and chemo-computational shell. This tool box will permit the identification of signal transduction mediators and/or transcriptional regulators responsible for certain changes or responses within a cell and in particular, those that lead to disease. In this way, this tool box will facilitate the discovery of new drug targets as well as aid the rational design of target-specific drugs.
PRD College is a Poverty Related Diseases College created in 2007 by a consortium of 10 fellows drawn from 5 countries in Africa (Cameroon, South Africa, Uganda, Zambia & Tanzania) and 4 countries in Europe (Germany, Sweden, The Netherlands & The Italy). It is an Interactive Programme in BioMedicine and Development, a virtual institute and a network that connects young African and European biomedical scientists and their institutions – fired with the zeal to consolidate science and its role in the overall development of Africa.
Researchers of all disciplines, from Life Sciences and Astronomy to Computational Chemistry, create and use ever-increasing amounts of complex data, and rely more and more on compute-intensive modelling, simulation and analysis. Scientific workflows have become a key paradigm for managing complex tasks and have emerged as a unifying mechanism for handling scientific data. Workflows capture the essence of the scientific process, providing a means to describe it via logical data- or work-flows. Workflows are mapped onto concrete Distributed Computing Infrastructures (DCIs) to perform large-scale experiments. The learning curve for reusing workflows, however, is still steep because workflows typically have their own user interfaces/APIs, description languages, provenance strategies, and enactment engines, which are not standard and do not interoperable. Workflow integration or reuse therefore is currently impractical, thereby inhibiting the growth in uptake and proliferation of workflows in scientific practice.
MIUR - FIRB:
LIBI: "International Laboratory for Bioinformatics"
"Public-Private Laboratory for Bioinformatics applied to Genomics".
MIUR - PON:
" Laboratorio di bioinformatica per la biodiversità molecolare".
" B.I.G.: Strengthening of the Bioinformatic and Genomic Infrastructures" – Prot. MIUR 3078/80
" Biosistema: Centro di Competenza in Biologie Avanzate"
MIUR PON, Ricerca Industriale
" MICROMAP: Sviluppo di una piattaforma tecnologica multiplex per diagnostica molecolare, portatile ed automatizzata, basata sulla logica strumentale del Lab-on-chip, in grado di consentire applicazioni multiparametriche in campo infettivologico"
"VIRTUALAB: Advanced Biomedical Mechatronic Systems for Diagnosis and Therapy based on Virtual and Augmented Reality, microelectronics and on high throughput robotised workstations"
Progetto Fondazione Cassa di Risparmio di Puglia:" Sviluppo di una nuova terapia antitumorale basata su biopeptidi in grado di ripristinare l'attività dell'oncosoppressore p53"
MIUR-Cluster : "Study of genes of biomedical and agro-food "
MIUR/PRIN :" A new method of analysing biodiversity: an application of pyrosequencing to the study of soil organisms".
FISM : "Large-scale analysis of infectious agents associated with Multiple Sclerosis through random and massive cDNA sequencing"
Regional Strategic – Puglia : "Research and Development of new Bioinformatic and Biotechnology instruments for the analysis of gene and protein expression profile of cancer and for the identification of biological markers to early diagnose colorectal, kidney and oral cavity neoplasia"
Infrastrutture Regionali – Puglia : "BioBancaOncologicaPugliese(BioBOP)-Network per l'utilizzo di tessuti oncologici controllati e caratterizzati per lo sviluppo di nuovi approcci Diagnostici, Farmacologici e Biomedicali"