Alessandra Mezzelani

The information published in this page are entirely managed by ALESSANDRA MARIA MEZZELANI who is completely responsible for it.

PhD Veterinary Biotechnologies

Current position (since 2001): staff researcher at the National Research Council, Institute of Biomedical Technologies (CNR-ITB), Segrate, Milan, Italy

Previous positions: 1995-2001: associated researcher at National Institute of Tumors, Milan, Italy 1992-1995: PhD student, ETH Zurich, Switzerland and CNR-IBBA, Milan, Italy 1989-1992: fellow, CNR-IBBA, Milan, Italy

Interest areas:

Research Fields and activities "Multi-omics" research in autism. She leads the CNR Unit of the European GEMMA Project She is responsible of the Single Cell Analysis (SCA) Unit and is applying SCA to breast cancer and viral infections. She represents CNR-ITB at the EU LifeTime Initiative to improve European healthcare through cell-based interceptive medicine. She is responsible of the Translational Bioinformatics Lab. to produce "omics" data or to validate bioinformatic results and predictions. She has a great experience in the usage of the common molecular biology techniques (RT-PCR, digital PCR, microarrays, preparation of Illumina libraries). She collaborates with the Faculty of Veterinary Medicine, University of Milan, to study diseases common to cats and humans. She is also involved in studies and activities of CNR about communication and accessibility.

She previously leaded the OTANEXT-AUT project (Interomics Flagship) and the Genetics Unit of the Health Minister GR-09 1570296 project, to investigate the role of mycotoxins in autism onset by a gene-environment interaction perspective. She took part in cancer studies and participated in the PON project VIRTUALAB and in AIRC projects for the discovery of biomarkers of soft tissue sarcomas As for agricultural field, she participated in the EU projects DNA-Track and BovMap.


Phone: 0226422606
Fax: 0226422770
Address: CNR-ITB Via Fratelli Cervi 93, 20090 Segrate (MI)

International Ids


Google Scholar H-Index: 29
Scopus H-Index: 23
ISI-WoS H-Index: 22


ricercatore III livello T.D.
Company: CNR - Consiglio Nazionale delle Ricerche - CNR P.le Aldo Moro 7 Roma
Time period: 10/2001 - today

ricercatore III livello
Company: CNR - Consiglio Nazionale delle Ricerche - CNR P.le Aldo Moro 7 Roma
Time period: 12/2005 - today

borsa di studio di chiara fama
Company: Università degli Studi di Milano - CISI- Via Fantoli 16/15
Company web site:
Time period: 06/2004 - 05/2005

ricercatore associato
Company: Istituto Nazionale dei Tumori di Milano
Time period: 10/1995 - 09/2001

Company: CNR - Consiglio Nazionale delle Ricerche
Time period: 1989 - 1992


Scientific projects

The relationship among food, mycotoxins, gastrointestinal disorders and au- tism: a multidisciplinary approach for the molecular investigation.
Role: Responsabile Unità Operativa
Participation time period: 12/2011 - 11/2015

Sistemi Avanzati di Meccatronica Biomedicale di Diagnosi e Terapia Medica basati su Realtà Virtuale e Aumentata, Microelettronica, e su Laboratori robotizzati ad elevato throughput.
Role: Responsabile dello sviluppo di un sistema diagnostico automatizzabile per la surgery navigation del linfonodo sentinella nei tumori testa collo
Participation time period: 07/2011 - 06/2015


Production Understanding
Written Oral Written Oral Notes
English - Professional working proficiency

Research activities classification (ERC)




Research products

Cupaioli Francesca Anna1, Corrivetti Giulio2, Tamburro Ilaria3, Fasano Alessio4, Mezzelani Alessandra1*

Change of Communication Strategy to Increase Engagement during the SARS-Cov-2Pandemic: The Experience of the European GEMMA Project in Italy

(2020) in International Journal of Humanities Social Sciences and Education
Troisi, Jacopo; Autio, Reija; Beopoulos, Thanos; Bravaccio, Carmela; Carraturo, Federica; Corrivetti, Giulio; Cunningham, Stephen; Devane, Samantha; Fallin, Daniele; Fetissov, Serguei; Gea, Manuel; Giorgi, Antonio; Iris, François; Joshi, Lokesh; Kadzielski, Sarah; Kraneveld, Aletta; Kumar, Himanshu; Ladd-Acosta, Christine; Leader, Geraldine; Mannion, Arlene; Maximin, Elise; Mezzelani, Alessandra; Milanesi, Luciano; Naudon, Laurent; Peralta Marzal, Lucia N.; Pardo, Paula Perez; Prince, Naika Z.; Rabot, Sylvie; Roeselers, Guus; Roos, Christophe; Roussin, Lea; Scala, Giovanni; Tuccinardi, Francesco Paolo; Fasano, Alessio

Genome, environment, microbiome and metabolome in autism (GEMMA) study design: Biomarkers identification for precision treatment and primary prevention of autism spectrum disorders by an integrated multi-omics systems biology approach

(2020) in Brain sciences
Francesca Anna Cupaioli1, Ettore Mosca 1, Chiara Magri 2, Massimo Gennarelli2,3, Marco Moscatelli1, Maria elisabetta Raggi4, Martina Landini1, Nadia Galluccio 1, Laura Villa4, Arianna Bonfanti4, Alessandra Renieri5,6, Chiara fallerini5, Alessandra Minelli2, Anna Marabotti 7, Luciano Milanesi 1, Alessio fasano 8,9 & Alessandra Mezzelani 1 ?

Assessment of haptoglobin alleles in autism spectrum disorders

(2020) in Scientific report (Camb. Res. Inst. (G.B.))
F.A. Cupaioli1, E Mosca1, N. Di Nanni1, P. Pelucchi1, L. Milanesi1, M.E. Raggi2, M.L. Villa2, A. Mezzelani1

Linked-read whole genome sequencing reveals undetected variants in autism spectrum disorder

(2020) European Human Genetics Virtual Conference ESHG 2020.2, JUNE 6-9, 2020
Cupaioli FA, Di Nanni N, Pelucchi P, Cifola I, Villa L, Raggi ME, Milanesi L, Mosca M, Mezzelani A

Linked read sequencing reveals new genetic variants in autism

(2020) Neurogenetics, Nature Conferences, Virtual (Covid19), 29/07/2020
Chiappori F, Cupaioli F.A., Milanesi L., Raggi M.E., Mezzelani A.

Microbiota Profile in Autism Spectrum Disorder: Different Metagenomics Approaches to analyze 16S and 18S rRNA

(2020) EPTRI open meeting 2020, virtuale (causa Covid19), April 2-3, 2020
F.A. Cupaioli, E. Mosca, N. Di Nanni, P. Pelucchi, L. Milanesi, M.E. Raggi, L. Villa, A. Mezzelani

Autism Spectrum Disorder: Linked-Read Sequencing Reveals New and Undetected Variants

(2020) EPTRI (European Paediatric Translational Research Infrastructure) open meeting 2020, virtual meeting, 02/04/2020 - 03/04/2020
Alessandra Mezzelani (oral presentation) F. A. Cupaioli1, E. Mosca1, N. Di Nanni1, P. Pelucchi1, L. Milanesi1, M. E. Raggi2, L. Villa2, A. Mezzelani1

Oral communication: Autism Spectrum Disorder: Linked-Read Sequencing Reveals New and Undetected Variants

Alessandra Mezzelani (oral presentation) (2020) EPTRI Open Meeting 2020, comunicazione orale on line (causa pandemia Covid19), 2-3/04/2020
Mezzelani, A.; Cupaioli, F. A.; Mosca, E.; Magri, C.; Gennarelli, M.; Raggi, M. E.; Landini, M.; Galluccio, N.; Chiappori, F.; Moscatelli, M.; Gnocchi, M.; Villa, C.; Molteni, M.; Bonfanti, A.; Ciceri, F.; Marabotti, A.; Milanesi, L.

Association of Haptoglobin-1 allele with Autism

(2019) in European journal of human genetics
Alessandra Mezzelani

Autismo: il coordinatore del progetto GEMMA alla conferenza internazionale "Dr. Roger's Prize"

Visualize all the publications (since 2016)