The ITB is the largest institute of its kind in Italy and was established to pioneer new types of cross-disciplinary biomedical research by bringing biology, engineering, medicine, and the basic sciences together. This is achieved by means of collaborations between industry and basic scientists and clinicians from a broad range of disciplines. One of the most important aims of its research mission is translating fundamental discoveries into new technologies.The Core Research Overview and the major focuses of the institute are: Cancer/Stem Cell research, Neurodegenerative Diseases, Cardiovascular medicine and Immunology combined with the development of high-throughput bioscience research such as Micro-Array and Proteomic-based technologies, novel high-throughput sequencing projects and Bioinformatics.