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Gomes-Filho, Sandro Mascena; dos Santos, Edmilson Ozorio; Matos Bertoldi, Ester Riserio; Scalabrini, Luiza Coimbra; Heidrich, Vitor; Dazzani, Bianca; Levantini, Elena; Reis, Eduardo Moraes; Basseres, Daniela Sanchez
Aurora A kinase and its activator TPX2 are potential therapeutic targets in KRAS-induced pancreatic cancer
(2020) in Cellulair oncology (2011. Print)
Chin T.-M.; Boopathy G.T.K.; Man E.P.S.; Clohessy J.G.; Csizmadia E.; Quinlan M.P.; Putti T.; Wan S.-C.; Xie C.; Ali A.; Wai F.C.; Ong Y.S.; Goh B.-C.; Settleman J.; Hong W.; Levantini E.; Tenen D.G.
Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors
(2020) in Theranostics
Felipe Silva Rodrigues, Vanessa Silva Miranda, Tatiana Correa Carneiro-Lobo, Luiza Coimbra Scalabrini, Bjorn Kruspig, Elena Levantini, Daniel J. Murphy, Daniela Sanchez Bassères
IKKb kinase promotes stemness, migration, and invasion in KRAS-driven lung adenocarcinoma cells
(2020) in International journal of molecular sciences (Online)
Carneiro-Lobo T.C.; Scalabrini L.C.; Magalhaes L.D.S.; Cardeal L.B.; Rodrigues F.S.; dos Santos E.O.; Baldwin A.S.; Levantini E.; Giordano R.J.; Basseres D.S.
IKKbeta targeting reduces KRAS-induced lung cancer angiogenesis in vitro and in vivo: A potential anti-angiogenic therapeutic target
(2019) in Lung cancer
Ali A, Levantini E, Fhu CW, Teo JT, Clohessy JG, Goggi JL, Wu CS, Chen L, Chin TM, Tenen DG1.
CAV1-GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer
(2019) in Theranostics
Barbara Storti, Simone Civita, Paolo Faraci, Giorgia Maroni, Indira Krishnan, Elena Levantini, Ranieri Bizzarri
Fluorescence imaging of biochemical relationship between ubiquitinated histone 2A and Polycomb complex protein BMI1
(2019) in Biophysical chemistry (Print)
Zilionis R, Engblom C, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ, Klein AM
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
(2019) in Immunity (Camb. Mass.)
Giorgia Maroni, Daniele Panetta, Raffaele Luongo, Indira Krishnan, Federica La Rosa, Daniela Campani, Piero Salvadori, Patricia Iozzo, Francesco Blasi, Dmitry Penkov, Elena Levantini, and Maria Cristina Magli.
The Role of Prep1 in the Regulation of Mesenchymal Stromal Cells
(2019) in International journal of molecular sciences (Print)
Ali A.; Levantini E.; Teo J.T.; Goggi J.; Clohessy J.G.; Wu C.S.; Chen L.; Yang H.; Krishnan I.; Kocher O.; Zhang J.; Soo R.A.; Bhakoo K.; Chin T.M.; Tenen D.G.
Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer
(2018) in EMBO molecular medicine (Print)
Gonzalez, David; Luyten, Annouck; Bartholdy, Boris; Zhou, Qiling; Kardosova, Miroslava; Ebralidze, Alex; Swanson, Kenneth D.; Radomska, Hanna S.; Zhang, Pu; Kobayashi, Susumu S.; Welner, Robert S.; Levantini, Elena; Steidl, Ulrich; Chong, Gilbert; Collombet, Samuel; Choi, Min Hee; Friedman, Alan D.; Scott, Linda M.; Alberich-Jorda, Meritxell; Tenen, Daniel G.
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPa
(2017) in Journal of biological chemistry (Online)
Patnaik A.; Swanson K.D.; Csizmadia E.; Solanki A.; Landon-Brace N.; Gehring M.P.; Helenius K.; Olson B.M.; Pyzer A.R.; Wang L.C.; Elemento O.; Novak J; Thornley T.B.; Asara J.M.; Montaser L.; Timmons J.J.; Morgan T.M.; Wang Y.; Levantini E.; Clohessy J.G.; Kelly K.; Pandolfi P.P.; Rosenblatt J.M.; Avigan D.E.; Ye H.; Karp J.M.; Signoretti S.; Balk S.P.; Cantley L.C.
Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Anti-Tumor Innate Immunity.
(2017) in Cancer discovery (Online)
Maroni, Giorgia; Tkachuk, Vsevolod A.; Egorov, Alexander; Morelli, Marco J.; Luongo, Raffaele; Levantini, Elena; Blasi, Francesco; Magli, Maria Cristina; Penkov, Dmitry
Prep1 prevents premature adipogenesis of mesenchymal progenitors
(2017) in Scientific reports (Nature Publishing Group)
Bonifer C.; Levantini E.; Kouskoff V.; Lacaud G.
Runx1 structure and function in blood cell development
(2017) , 2017
Yong K.J.; Basseres D.S.; Welner R.S.; Zhang W.C.; Yang H.; Yan B.; Alberich-Jorda M.; Zhang J.; De Figueiredo-Pontes L.L.; Battelli C.; Hetherington C.J.; Ye M.; Zhang H.; Maroni G.; O'Brien K.; Magli M.C.; Borczuk A.C.; Varticovski L.; Kocher O.; Zhang P.; Moon Y.-C.; Sydorenko N.; Cao L.; Davis T.W.; Thakkar B.M.; Soo R.A.; Iwama A.; Lim B.; Halmos B.; Neuberg D.; Tenen D.G.; Levantini E.
Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPa expression
(2016) in Science translational medicine
dos Santos, Edmilson Ozorio; Carneiro-Lobo, Tatiana Correa; Aoki, Mateus Nobrega; Levantini, Elena; Basseres, Daniela Sanchez
Aurora kinase targeting in lung cancer reduces KRAS-induced transformation
(2016) in Molecular cancer
Bararia D.; Kwok H.S.; Welner R.S.; Numata A.; Sarosi M.B.; Yang H.; Wee S.; Tschuri S.; Ray D.; Weigert O.; Levantini E.; Ebralidze A.K.; Gunaratne J.; Tenen D.G.
Acetylation of C/EBPa inhibits its granulopoietic function
(2016) in Nature communications
Y Cai, A Hirata, S Nakayama, PA VanderLaan, E. Levantini, M. Yamamoto, H. Hirai, DB Costa, H Watanabe, S S Kobayashi
CCAAT/Enhancer Binding Protein beta is Dispensable for Development of Lung Adenocarcinoma
(2015) in PloS one
Welner, Robert S.; Amabile, Giovanni; Bararia, Deepak; Czibere, Akos; Yang, Henry; Zhang, Hong; Pontes, Lorena Lobo De Figueiredo; Ye, Min; Levantini, Elena; Di Ruscio, Annalisa; Martinelli, Giovanni; Tenen, Daniel G.
Treatment of Chronic Myelogenous Leukemia by Blocking Cytokine Alterations Found in Normal Stem and Progenitor Cells
(2015) in Cancer cell (Print)
Amabile, Giovanni; Di Ruscio, Annalisa; Mueller, Fabian; Welner, Robert S.; Yang, Henry; Ebralidze, Alexander K.; Zhang, Hong; Levantini, Elena; Qi, Lihua; Martinelli, Giovanni; Brummelkamp, Thijn; Le Beau, Michelle M.; Figueroa, Maria E.; Bock, Christoph; Tenen, Daniel G.
Dissecting the role of aberrant DNA methylation in human leukaemia
(2015) in Nature communications
Ye, Min; Zhang, Hong; Yang, Henry; Koche, Richard; Staber, Philipp B.; Cusan, Monica; Levantini, Elena; Welner, Robert S.; Bach, Christian S.; Zhang, Junyan; Krivtsov, Andrei V.; Armstrong, Scott A.; Tenen, Daniel G.
Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia
(2015) in Cell stem cell (Print)
Philipp Bernhard Staber, Pu Zhang, Min Ye, Robert S Welner, Elena Levantini, Annalisa DiRuscio, Alexander K Ebralidze, Christian Bach, Hong Zhang, Junyan Zhang, Katrina Vanura, Ruud Delwel, Henry Yang, Gang Huang, and Daniel G. Tenen
The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells
(2014) in Blood (Online)
Zhang, Hong; Alberich-Jorda, Meritxell; Amabile, Giovanni; Yang, Henry; Staber, Philipp B.; Di Ruscio, Annalisa; Weiner, Robert S.; Ebralidze, Alexander; Zhang, Junyan; Levantini, Elena; Lefebvre, Veronique; Valk, Peter J. M.; Delwel, Ruud; Hoogenkamp, Maarten; Nerlov, Claus; Cammenga, Joerg; Saez, Borja; Scadden, David T.; Bonifer, Constanze; Ye, Min; Tenen, Daniel G.
Sox4 Is a Key Oncogenic Target in C/EBP alpha Mutant Acute Myeloid Leukemia (vol 24, pg 575, 2013)
(2013) in Cancer cell (Print)
Peter, Yakov; Sen, Namita; Levantini, Elena; Keller, Steven; Ingenito, Edward P.; Ciner, Aaron; Sackstein, Robert; Shapiro, Steven D.
CD45/CD11b positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture
(2013) in Journal of tissue engineering and regenerative medicine
Ye, Min; Zhang, Hong; Amabile, Giovanni; Yang, Henry; Staber, Philipp B.; Zhang, Pu; Levantini, Elena; Alberich-Jorda, Meritxell; Zhang, Junyan; Kawasaki, Akira; Tenen, Daniel G.
C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence
(2013) in Nature cell biology
Blanchet MR., Bennett JL., Gold MJ., Levantini E., Tenen DG., Girard M., Cormier Y., and McNagny KM
CD34 is required for dendritic cell trafficking and pathology in murine hypersensitivity pneumonis
(2011) in American journal of respiratory and critical care medicine
Elena Levantini, Sanghoon Lee, Hanna S. Radomska, Christopher J. Hetherington, Meritxell Alberich-Jorda, Giovanni Amabile, Pu Zhang, David Gonzalez, Junyan Zhang, Daniela S. Basseres, Nicola K. Wilson, Steffen Koschmieder, Gang Huang, Dong-Er Zhang, Alexander K. Ebralidze, Constanze Bonifer, Yutaka Okuno, Bertie Gottgens, Daniel G. Tene
RUNX proteins regulate gene expression in long-term hematopoietic stem cells by mediating interaction of distal and proximal regulatory elements
(2011) in EMBO journal (Print)
O'Brien K., Alberich-Jorda' M., Yadav N., Kocher O., Di Ruscio A., Ebralidze A., Levantini E., Sng NJL., Bhasin M., Caron T., Kim D., Steidl U., Huang G., Halmos B., Rodig SJ., Bedfords MT., Tenen DG., Kobayashi S
CARM1 (PMRT4) is required for proper control of proliferation and differentiation of pulmonary epithelial cells
(2010) in Development (Camb.)
Basseres S Daniela, Ebbs Aaron, Levantini Elena, Baldwin Albert S
Requirement of the NF-kB subunit p65/RelA for K-Ras-induced lung tumorigenesis
(2010) in Cancer research (Chic. Ill.)
Koschmieder S.; Halmos B.; Levantini E.; Tenen D.G.
Dysregulation of the C/EBPa differentiation pathway in human cancer
(2009) in Journal of clinical oncology
Guibal F.C.; Alberich-Jorda M.; Hirai H.; Ebralidze A.; Levantini E.; Di Ruscio A.; Zhang P.; Santana-Lemos B.A.; Neuberg D.; Wagers A.J.; Rego E.M.; Tenen D.G.
Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia
(2009) in Blood (Online)
Peter Y.; Comellas A.; Levantini E.; Ingenito E.P.; Shapiro S.D.
Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: Implications for non-small cell lung cancer tumor colonization
(2009) in Molecular carcinogenesis (Online)
Koschmieder S, D'Alo' F, Radomska H, Schöneich C, Chang J-S, Konopleva M, Kobayashi S, Levantini E, Suh N, Di Roscio A, Voso MT, Watt JC, Santhanam R, Sargin B, Kantarijan H, Andreeff M, Sporn MB, Perrotti D, Berdel WE, Müller-Tidow C, Serve H, Tenen DG
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational upregulation of p42 CCAAT enhancer binding protein alpha
(2007) in Blood (Online)
Basseres D.S.; Levantini E.; Ji H.; Monti S.; Elf S.; Dayaram T.; Fenyus M.; Kocher O.; Golub T.; Wong K.-K.; Halmos B.; Tenen D.G.
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPa in mice
(2006) in Molecular and cellular biology (Print)
Kubo S, Levantini E, Kobayashi S, Kocher O, Halmos B, Tenen DG, Takahashi M
In vivo three-dimensional magnetic resonance microscopy of pulmonary solitary tumors in transgenic mice
(2006) in Magnetic resonance in medicine (Online)
Zhang P, Iwasaki-Arai J, Iwasaki H, Fenyus ML, Dayaram T, Owens BM, Shigematsu H, Levantini E, Huettner CS, Lekstrom-Himes JA, Akashi K, Tenen DG
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor CCAAT Enhancer Binding protein a
(2004) in Immunity (Camb. Mass.)
Cairns L.A.; Moroni E.; Levantini E.; Giorgetti A.; Klinger F.G.; Ronzoni S.; Tatangelo L.; Tiveron C.; De Felici M.; Dolci S.; Magli M.C.; Giglioni B.; Ottolenghi S.
Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages
(2003) in Blood
Levantini E.; Giorgetti A.; Cerisoli F.; Traggiai E.; Guidi A.; Martin R.; Acampora D.; Aplan P.D.; Keller G.; Simeone A.; Iscove N.N.; Hoang T.; Magli M.C.
Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis
(2003) in Proceedings of the National Academy of Sciences of the United States of America
Magli MC, Levantini E, Giorgetti A.
Developmental potential of somatic stem cells in mammalian adults
(2000) in Journal of hematotherapy & stem cell research
Revoltella R.P.; Laricchia Robbio L.; Vikinge T.; Pardi E.; Levantini E.; Beffy P.
Human GM-CSF interaction with the ?-chain of its receptor studied using surface plasmon resonance
(1999) in Biosensors & bioelectronics
