Eva Pinatel

Eva Maria Pinatel is researcher at ITB-CNR in Segrate (Milan). She is author of 18 publications cited in more than 500 research papers, her h-index is 10. She focused her research activity on -omic technologies based investigation of biological processes, starting with microarray and ending up with next generation sequencing (NGS). At the beginning of her career she studied microRNAs role in tumor progression both in vitro and in silico. Then she moved to the investigation of gene expression control in bacteria, applied both to antibiotics production increase and to the study of host-pathogen interaction. On this topic she recently started an integrated study of the interactions between environment (pollution) , nasal microbiota and host susceptibility and response to viral infections. Finally, she is also involved in the study of genome accessibility through new NGS-based technologies (SAMMY-seq) and to their comparison with pre-existent techniques.

Next generation sequencing data analysis and integration of Chip-seq, RNA-seq and SAMMY-seq data both in human and bacterial samples. MiRNA target prediction analysis and integration with gene expression data or interaction networks.

Expression profiling of microRNAs and isomiRs in conventional central chondrosarcoma

Helicobacter pylori Stress-Response: Definition of the HrcA Regulon

Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis.

G4PromFinder: an algorithm for predicting transcription promoters in GC-rich bacterial genomes based on AT-rich elements and G-quadruplex motifs

RNA Sequencing and Analysis in Microorganisms for Metabolic Network Reconstruction.

Pseudomonas aeruginosa mutants defective in glucose uptake have pleiotropic phenotype and altered virulence in non-mammal infection models

Pirin: a novel redox-sensitive modulator of primary and secondary metabolism in Streptomyces.

The Helicobacter pylori Heat-Shock Repressor HspR: Definition of Its Direct Regulon and Characterization of the Cooperative DNA-Binding Mechanism on Its Own Promoter

Induced pluripotent stem cells-derived extracellular vesicles shuttle bioactive molecules with anti-fibrotic potential in vitro and in vivo

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines.

Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

Time-Resolved Transcriptomics and Constraint-Based Modeling Identify System-Level Metabolic Features and Overexpression Targets to Increase Spiramycin Production in Streptomyces ambofaciens

Comprehensive mapping of the Helicobacter pylori NikR regulon provides new insights in bacterial nickel responses

Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns

Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-?

IDENTIFICATION OF H. PYLORI EPITOPES RESPONSIBLE FOR HOST IMMUNO-RESPONSE MODULATION THROUGH ORF-FILTERED PHAGE DISPLAY LIBRARIES AND INTERACTOME-SEQUENCING