Gianluca De Bellis

My main interest is in the DNA analysis technologies and applications. Since 2004 I am involved in Next Generation Sequencing technologies and applications

Next Generation Sequencing, NGS Data Analysis, DNA analysis

CV

A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia

InteractomeSeq: a web server for the identification and profiling of domains and epitopes from phage display and next generation sequencing data

A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia

Candidate Genes and MiRNAs Linked to the Inverse Relationship Between Cancer and Alzheimer's Disease: Insights From Data Mining and Enrichment Analysis

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer

Pirin: a novel redox-sensitive modulator of primary and secondary metabolism in Streptomyces.

A census of tandemly repeated polymorphic loci in genic regions through the comparative integration of human genome assemblies

A combination of top-down and bottom-up approaches addressing the inverse occurrence of Alzheimer's disease and cancer enables to classify patients based on their genotypes

Combining epidemiological and in silico investigations to elucidate the genetic basis of the inverse occurrence between Alzheimer's disease and cancer

MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences

Retroviral Scanning: Mapping MLV Integration Sites to Define Cell-specific Regulatory Regions.

Comprehensive mapping of the Helicobacter pylori NikR regulon provides new insights in bacterial nickel responses

WoPPER: Web server for Position Related data analysis of gene Expression in Prokaryotes.

Complete mitochondrial sequences from Mesolithic Sardinia

Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites

Time-Resolved Transcriptomics and Constraint-Based Modeling Identify System-Level Metabolic Features and Overexpression Targets to Increase Spiramycin Production in Streptomyces ambofaciens

Identification and characterization of multiple sclerosis associated loci in the continental italian population

ICESpy009, a conjugative genetic element carrying mef(E) in Streptococcus pyogenes

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

Next generation sequencing of pooled samples: Guideline for variants' filtering

Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation

Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment

Behçet's syndrome patients exhibit specific microbiome signature

High-throughput genetic characterization of a cohort of Brugada syndrome patients

Antifungal activity improved by coproduction of cyclodextrins and anabaenolysins in Cyanobacteria

Characterization of the escherichia coli ?S core regulon by chromatin immunoprecipitation-sequencing (ChIP-seq) analysis

The Neanderthal in the karst: First dating, morphometric, and paleogenetic data on the fossil skeleton from Altamura (Italy)

Genome-wide definition of promoter and enhancer usage during neural induction of human embryonic stem cells

The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs

Characterization of the Escherichia coli ?S core regulon by Chromatin Immunoprecipitation-sequencing (ChIP-seq) analysis

Gut microbiota trajectory in pediatric patients undergoing hematopoietic SCT

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns

A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon Actinomycete

Identification of novel proteins binding the AU-rich element of ?-prothymosin mRNA through the selection of open reading frames (RIDome)

Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia.

T cell neo-epitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes

Target resequencing of regions associated with multiple sclerosis in the Italian population

Structural Variations Identified By Whole Transcriptome Sequencing (RNA-Seq) in Childhood ALL with Different Response to Therapy

Enly: Improving Draft Genomes through Reads Recycling.

Comparative genomics revealed key molecular targets to rapidly convert a reference rifamycin-producing bacterial strain into an overproducer by genetic engineering

Positioning the red deer (Cervus elaphus) hunted by the Tyrolean Iceman into a mitochondrial DNA phylogeny

Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer

Small noncoding RNAs in cells transformed by human T-cell leukemia virus type 1: A lole for a tRNA fragment as a primer for reverse transcriptase

Gut microbiome of the Hadza hunter-gatherers

Genome-wide analysis of alpharetroviral integration in human hematopoietic stem/progenitor cells.

Gene and Protein Expression in Response to Different Growth Temperatures and Oxygen Availability in Burkholderia thailandensis

Draft Genome Sequence of the Host-Restricted Salmonella enterica Serovar Abortusovis Strain SS44.

Self-inactivating alpharetroviral vectors have a low genotoxic integration profile in human CD34(+) hematopoietic progenitor cells

Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL

The Enterocyte-Associated Intestinal Microbiota of Breast-Fed Infants and Adults Responds Differently to a TNF-alpha-Mediated Pro-Inflammatory Stimulus

Whole Genome SNP Genotyping and Exome Sequencing Reveal Novel Genetic Variants and Putative Causative Genes in Congenital Hyperinsulinism

Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms

Ancient DNA studies: new perspectives on old samples (vol 44, pg 21, 2012)

Profiling celiac disease antibody repertoire

Comprehensive Genomic Characterization of Cutaneous Malignant Melanoma Cell Lines Derived from Metastatic Lesions by Whole-Exome Sequencing and SNP Array Profiling

Origins and Evolution of the Etruscans' mtDNA

The genome sequence of the hydrocarbon-degrading Acinetobacter venetianus VE-C3

Expression profiling of genes involved in the formation of aroma in two peach genotypes

Deletion of the LTR Enhancer/Promoter Has No Impact on the Integration Profile of MLV Vectors in Human Hematopoietic Progenitors

An efficient rRNA removal method for RNA sequencing in GC-rich bacteria.

EXCAVATOR: Detecting copy number variants from whole-exome sequencing data

Genome-wide analysis of promoter and enhancer usage in hematopoietic stem cell differentiation.

Self-inactivating and wild-type MLV vectors share the same integration profile in human CD34+hematopoietic progenitor cells but not in human epidermal keratinocytes

Specific inactivation of two immunomodulatory SIGLEC genes during human evolution

The tomato genome sequence provides insights into fleshy fruit evolution

Unbalance of intestinal microbiota in atopic children

Ancient DNA studies: new perspectives on old samples

Detection and characterization of pathogenic vibrios in shellfish by a Ligation Detection Reaction-Universal Array approach

Diversity of bifidobacteria within the infant gut microbiota.

Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain.

Phylogenetic Position of a Copper Age Sheep (Ovis aries) Mitochondrial DNA.

The tomato genome sequence provides insights into fleshy fruit evolution.

Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain

Self-inactivating and wild-type MLV vectors have the same integration profile in human CD34(+) hematopoietic progenitor cells

A BIOINFORMATIC APPROACH FOR NGS DATA TO ANALIZE AND VISUALIZE CHROMOSOMAL FUSION EVENTS IN HUMAN BREAST CANCER.

Array Platform for Food Safety and Quality

Array Platform for Food Safety and Quality

Defining the lentiviral integrome in human hematopoietic cells

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

In vitro transcription profiling of the Sigma(S) subunit of bacterial RNA polymerase: re-definition of the Sigma(S) regulon and identification of Sigma(S)-specific promoter sequence elements

Complete genome sequence of a serotype 11A, ST62 Streptococcus pneumoniae invasive isolate.

The Complete Mitochondrial Genome of an 11,450-year-old Aurochsen (Bos primigenius) from Central Italy

Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms

In vitro transcription profiling of the ?S subunit of bacterial RNA polymerase: re-definition of the ?S regulon and identification of ?S-specific promoter sequence elements

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

Advances in DNA Microarray Technology for the Detection of Foodborne Pathogens

Deep sequencing reveals double mutations in cis of MPL exon 10 in myelloproliferative neoplasm's

Sequenze di microRNA individuate in popolazioni e sub-popolazioni ematiche

High taxonomic level fingerprint of the human intestinal microbiota by Ligase Detection Reaction - Universal Array approach

Reliable resequencing of the human dystrophin locus by universal long polymerase chain reaction and massive pyrosequencing

Rapid interactome profiling by massive sequencing

High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors

The Microcephalin Ancestral Allele in a Neanderthal Individual

Characterization of Nucleotide Misincorporation Patterns in the Iceman's Mitochondrial DNA

Rapid interactome profiling by massive sequencing

The transcriptional complexity of cancer: a breast cancer experience

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing.

Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production

High-resolution profiling of MLV integration in human CD34 cells reveals cell-specific transcriptional regulatory element

Cell-Specific Transcriptional Regulatory Domains Attract y-Retroviral Integration in the Human Genome

ORMA: a tool for identification of species-specific variations in 16S rRNA gene and oligonucleotides design

Disposable plastic microreactors for genomic analyses Biomed Microdevices

Development of a LDR-Universal array platform for the phylogenetic fingerprint of the Human Intestinal Microbiota

Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group

Identification of hepatotoxin-producing cyanobacteria by DNA-chip

Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group.

Anchoring of unmodified oligonucleotides on a chitosan-based array: applications to genotyping and gene expression

Methods for detection of GMOs in food and feed,

Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

Complete mitochondrial genome sequence of the Tyrolean Iceman

A procedure for olive oil traceability and authenticity: DNA extraction, multiplex PCR and LDR-universal array analysis

Olive variety identification by ligation detection reaction in a universal array format

Complete gene expression profiling of Saccharopolyspora erythraea using GeneChip DNA microarrays.

Data handling strategies for high throughput pyrosequencers.

Transcriptome amplification methods in gene expression profiling.

A Structured Chitosan-Based Platform for Biomolecule Attachment to Solid Surfaces: Application to DNA Microarray Preparation

Polymerase chain reaction of 2-kb cyanobacterial gene and human anti-alpha(1)-chymotrypsin gene from genomic DNA on the In-Check single-use microfabricated silicon chip.

Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

Strategies for comparing gene expression profiles from different microarray platforms: Application to a case-control experiment

Application of the Taguchi method to the analysis of the deposition step in microarray production.

Data handling strategies for high throughput pyrosequencers.

Microarray analysis applied to the study of milk protein loci in cattle

A Microarray Platform for Parallel Detection of Five Transgenic Events in Foods: A Combined Polymerase Chain Reaction?Ligation Detection Reaction Universal Array Method

Multiplex polymerase chain reaction and ligation detection reaction/universal array technology for the traceability of genetically modified organisms in foods

Detection of Genetically Modified Soybean Using Peptide Nucleic Acids (PNAs) and Microarray Technology

Polymorphism analysis within the HLA-A locus by universal oligonucleotide array

Detection and quantitation of genetically modified maize (Bt-176 transgenic maize) by applying ligation detection reaction and universal array technology.

Development of a universal microarray based on the ligation detection reaction and 16S rRNA gene polymorphism to target diversity of cyanobacteria

Method for detecting toxic and non toxic cyanobacteria

Use of peptide nucleic acids (PNAs) and microarrays for the detection of DNA sequences in food matrices

Investigation of human polymorphisms by Ligation Detection Reaction and Universal Array

Apolipoprotein E and transferrin genotyping by ligation detection reaction and universal array

Detection of HLA polymorphisms by ligase detection reaction and a universal array format: A pilot study for low resolution genotyping

Strategies and tools for upgrading the information content of regulated gene lists from microarray experiments

Transferrin C2 variant does confer a risk for Alzheimers disease in caucasian.

Application of microtechnology in biotechnology. Microarray analytical systems-an overview.

Detection of HLA polymorphisms by ligase detection reaction and a universal array format: a pilot study for low resolution genotyping

Strategies and tools for upgrading the information content of regulated genes lists from microarray experiments

Apolipoprotein E and transferrin genotyping by ligation detection reaction and universal array

Two efficient polymeric platforms for oligonucleotide microarray preparation.

Ligation detection reaction and universal array for detection and identification of genetically modified organisms (GMOs)

Ligase detection reaction and universal array as a tool to detect grapevine infecting phytoplasmas

Ligase detection reaction (LDR) and universal array (Zip Code): application to DNA genotyping

Investigation of the multiple anchors approach in oligonucleotide microarray preparation using linear and stem-loop structured probes.

Investigation of a subset of human polymorphisms by ligase detection reaction and universal array

Cross-species conservation of SEL1L, a human pancreas-specific expressing gene.

Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction).

Application of an universal DNA microarray to cyanobacterial diversity assessment

Investigation of the multiple anchors approach in oligonucleotide microarray preparation using linear and stem-loop structured probes

Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction)

Two efficient polymeric chemical platforms for oligonucleotide microarray preparation

Application of a Universal DNA Microarray to Cyanobacterial diversity assessment

Structured chemical platform for biomolecule attachment to solid surfaces

Development of oligonucleotide arrays to detect mutations and polymorphisms

Microelectrodes organized in a array format for biomolecular investigations

Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism

Electrospray mass spectrometry of synthetic oligonucleotides using 2-propanol and spermidine

Analysis of DNA microarrays by non-destructive fluorescent staining using SYBR green II.

Time-resolved DNA-microarray reading by an intensified CCD for ultimate sensitivity

Analysis of DNA microarrays by non-destructive fluorescent staining using SYBR green II.

PROGETTO PNR- Tema 9 "Strumentazione per le Biotecnologie Avanzate"- linea 1.3.2.2.

OLIGONUCLEOTIDES QUALITY CONTROL ANALYSIS IN FREE SOLUTION BY CAPILLARY ELECTROPHORESIS AT ACIDIC pH.

Composition dependent separation of oligonucleotides by capillary electrophoresis in acidic buffers with application to the quality control of synthetic oligonucleotides.

Microarray technology in molecular diagnosis and gene expression studies

Application of capillary electrophoresis at low pH to oligonucleotides quality control.

Sequence and gene content in 35 kb genomic clone mapping in the human Xq27.1 region.

Apolipoprotein E genotyping by capillary electrophoretic analysis of restriction fragments.

Oligonucleotide analysis by capillary zone electrophoresis at low pH

Identification of a U7snRNAhomologue mapping to the human Xq27.1 region between the DXS1232 and DXS119loci

A more stringent choice of primers can improve the performance of fluorescent automated DNA sequencers

Cloning of a gene encoding a Dnase I-like endonuclease in the human Xq28 region

Characterization of Hb Camperdown [beta 104(G6)Arg-->Ser] by capillary electrophoresis and automated solid phase DNA sequencing.

Multiple G6PD mutations are associated with a clinical and biochemical phenotype similar to that of G6PD Mediterranean.

Fluorescence-based automated DNA sequencing by limited primer labeling.

Anion-exchange HPLC analysis of biotinylated oligonucleotides.

Molecular characterisation of an Italian G6PD variant responsible for chronic non-spherocytic haemolytic anaemia.

Hb Agenogi [beta 90(F6)Glu-->Lys] identified by DNA analysis.

Mixed-mode fluorescent DNA sequencing.

Identification of novel putative genes in the human Xq27-28 region

Detection of human chromosomes in somatic cell hybrids by PCR analysis,

Hb Abruzzo beta 143 (H21) His>Arg. A high oxygen affinity variant identified by mass spectrometry and DNA analysis

A more stringent choice of primers can improve the performance of fluorescent automated DNA sequencers,

Dideoxy linear polimerase chain reaction on a commercial fluorescent automated DNA sequencer

Fluorescent automated sequencers: a file exchange program.

Dideoxy linear polimerase chain reaction on a commercial fluorescent automated DNA sequencer

The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein h-lamp2, and assigns the gene to Xq24

Primer design in fluorescent automated DNA sequencing

A fast atom bombardment-mass spectrometric method to quantitate lyso-phosphatidylserine in rat brain

Metabolism and pharmacokinetics of p-(3,3-dimethyl-1-triazeno) benzoic acid in M5076 sarcoma bearing mice

Development of a mass spectrometric method to quantitate platelet activating factor in mouse urine.