Le informazioni pubblicate in questa pagina sono gestite in completa autonomia da PASQUALINA D'URSI il/la quale se ne assume ogni responsabilità
Giagulli C.; Caccuri F.; Zorzan S.; Bugatti A.; Zani A.; Filippini F.; Manocha E.; D'Ursi P.; Orro A.; Dolcetti R.; Caruso A.
B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation
(2020) in Cancer gene therapy
Bella, Pamela; Farini, Andrea; Banfi, Stefania; Parolini, Daniele; Tonna, Noemi; Meregalli, Mirella; Belicchi, Marzia; Erratico, Silvia; D'Ursi, Pasqualina; Bianco, Fabio; Legato, Mariella; Ruocco, Chiara; Sitzia, Clementina; Sangiorgi, Simone; Villa, Chiara; D'Antona, Giuseppe; Milanesi, Luciano; Nisoli, Enzo; Mauri, PierLuigi; Torrente, Yvan
Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy
(2020) in EMBO molecular medicine (Print)
Rusnati, Marco; D'Ursi, Pasqualina; Pedemonte, Nicoletta; Urbinati, Chiara; Ford, Robert C.; Cichero, Elena; Uggeri, Matteo; Orro, Alessandro; Fossa, Paola
Recent Strategic Advances in CFTR Drug Discovery: An Overview
(2020) in International journal of molecular sciences (Online)
Bugatti A.; Paiardi G.; Urbinati C.; Chiodelli P.; Orro A.; Uggeri M.; Milanesi L.; Caruso A.; Caccuri F.; D'Ursi P.; Rusnati M.
Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications
(2019) in Scientific reports (Nature Publishing Group)
D'Ursi, Pasqualina; Uggeri, Matteo; Urbinati, Chiara; Millo, Enrico; Paiardi, Giulia; Milanesi, Luciano; Ford, Robert C.; Clews, Jack; Meng, Xin; Bergese, Paolo; Ridolfi, Andrea; Pedemonte, Nicoletta; Fossa, Paola; Orro, Alessandro; Rusnati, Marco
Exploitation of a novel biosensor based on the full-length human F508de1-CFTR with computational studies, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue
(2019) in Sensors and actuators. B, Chemical (Print)
Rusnati, Marco; Sala, Davide; Orro, Alessandro; Bugatti, Antonella; Trombetti, Gabriele; Cichero, Elena; Urbinati, Chiara; Di Somma, Margherita; Millo, Enrico; Galietta, Luis J. V.; Milanesi, Luciano; Fossa, Paola; D'Ursi, Pasqualina
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
(2018) in Molecules (Basel, Online)
Di Canito, Alessandra; Zampolli, Jessica; Orro, Alessandro; D'Ursi, Pasqualina; Milanesi, Luciano; Sello, Guido; Steinbuechel, Alexander; Di Gennaro, Patrizia
Genome-based analysis for the identification of genes involved in o-xylene degradation in Rhodococcus opacus R7
(2018) in BMC genomics
Fontana L1, Bedeschi MF2, Maitz S3, Cereda A4, Faré C5, Motta S5, Seresini A6,7, D'Ursi P8, Orro A8, Pecile V9, Calvello M5, Selicorni A10, Lalatta F2, Milani D11, Sirchia SM12, Miozzo M1,5, Tabano S1.
Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders
(2018) in Epigenetics (Online)
Giagulli, Cinzia; D'Ursi, Pasqualina; He, Wangxiao; Zorzan, Simone; Caccuri, Francesca; Varney, Kristen; Orro, Alessandro; Marsico, Stefania; Otjacques, Benoit; Laudanna, Carlo; Milanesi, Luciano; Dolcetti, Riccardo; Fiorentini, Simona; Lu, Wuyuan; Caruso, Arnaldo
A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17
(2017) in Scientific reports (Nature Publishing Group)
Brullo, Chiara; Ricciarelli, Roberta; Prickaerts, Jos; Arancio, Ottavio; Massa, Matteo; Rotolo, Chiara; Romussi, Alessia; Rebosio, Claudia; Marengo, Barbara; Pronzato, Maria Adelaide; van Hagen, Britt T J; van Goethem, Nick P.; D'Ursi, Pasqualina; Orro, Alessandro; Milanesi, Luciano; Guariento, Sara; Cichero, Elena; Fossa, Paola; Fedele, Ernesto; Fedele, Ernesto; Bruno, Olga
New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment
(2016) in European journal of medicinal chemistry
D'Ursi, Pasqualina; Guariento, Sara; Trombetti, Gabriele; Orro, Alessandro; Cichero, Elena; Milanesi, Luciano; Fossa, Paola; Bruno, Olga
Further Insights in the Binding Mode of Selective Inhibitors to Human PDE4D Enzyme Combining Docking and Molecular Dynamics
(2016) in Molecular informatics (Print)
Cappelletti, Martina; Fedi, Stefani; Zampolli, Jessica; Di Canito, Alessandra; D'Ursi, Pasqualina; Orro, Alessandro; Viti, Carlo; Milanesi, Luciano; Zannoni, Davide; Di Gennaro, Patrizia
Phenotype microarray analysis may unravel genetic determinants of the stress response by Rhodococcus aetherivorans BCP1 and Rhodococcus opacus R7
(2016) in Research in microbiology (Paris)
Orro, Alessandro; Cappelletti, Martina; D'Ursi, Pasqualina; Milanesi, Luciano; Di Canito, Alessandra; Zampolli, Jessica; Collina, Elena; Decorosi, Francesca; Viti, Carlo; Fedi, Stefano; Presentato, Alessandro; Zannoni, Davide; Di Gennaro, Patrizia
Genome and Phenotype Microarray Analyses of Rhodococcus sp BCP1 and Rhodococcus opacus R7: Genetic Determinants and Metabolic Abilities with Environmental Relevance
(2015) in PloS one
Pasqualina D'Ursi a*, Alessandro Orro a, Giulia Morra b, Marco Moscatelli ac, Gabriele Trombetti a, Luciano Milanesi a & Ermanna Rovida d*
Molecular dynamics and docking simulation of a natural variant of Activated Protein C with impaired protease activity: implications for integrin-mediated antiseptic function.
(2015) in Journal of biomolecular structure and dynamics (Online)
Guariento Sara, 1 , D'Ursi Pasqualina, 2, Fossa Paola, 1.
Exhaustive molecular dynamics on GPU architectures unveil side chain flexibilities in PDE4D catalytic site and suggest new opportunities for designing selectve inhibitors.
(2014) Computationally Driven Drug Discovery Meeting CDDD 3° Meeting, Verona, 4-6 Marzo
Di Gennaro, P; Zampolli, J; Presti, I; Cappelletti, M; D'Ursi, P; Orro, A; Mezzelani, A; Milanesi, L
Genome Sequence of Rhodococcus opacus Strain R7, a Biodegrader of Mono- and Polycyclic Aromatic Hydrocarbons.
(2014) in genome announcements
Cichero E, Espinoza S, Franchini S, D'Ursi P, Raul R. Gainetdinov R. R, Brasili L, Milanesi L and Fossa P.
Insights into the structure of the Human TAAR5 receptor: a computational study.
(2014) Computationally Driven Drug Discovery Meeting CDDD 3° Meeting, Verona, 4-6 marzo 2014
D'Ursi P., Orro A., Trombetti G., Milanesi L.
Long Molecular Dynamics on GPUs infrastructure establish key residues and the binding mode of the inhibitors of the phosphodiesterase superfamily.
(2013) 1° Bioinformatics, computational Biology and System Biology lombardy day BioLom 2013, Milano, 27 novembre 2013
Cichero, Elena; D'Ursi, Pasqualina; Moscatelli, Marco; Bruno, Olga; Orro, Alessandro; Rotolo, Chiara; Milanesi, Luciano; Fossa, Paola
Homology Modeling, Docking Studies and Molecular Dynamic Simulations Using Graphical Processing Unit Architecture to Probe the Type-11 Phosphodiesterase Catalytic Site: A Computational Approach for the Rational Design of Selective Inhibitors
(2013) in Chemical biology & drug design (Print)
Cappelletti, M; Di Gennaro, P; D'Ursi, P; Orro, A; Mezzelani, A; Landini, M; Fedi, S; Frascari, D; Presentato, A; Zannoni, D; Milanesi, L
Genome Sequence of Rhodococcus sp. Strain BCP1, a Biodegrader of Alkanes and Chlorinated Compounds.
(2013) in genome announcements
Bugatti A, Giagulli C, Urbinati C, Caccuri F, Chiodelli P, Oreste P, Fiorentini S, Orro A, Milanesi L, D'Ursi P, Caruso A, Rusnati M.
Molecular interaction studies of HIV-1 matrix protein p17 and heparin: identification of the heparin-binding motif of p17 as a target for the development of multitarget antagonists.
(2013) in The Journal of biological chemistry (Print)
Silvia Santoro1, Pasqualina D'Ursi1, Nadia Galluccio1, Martina Landini1, Alessandra Mezzelani1, Alessandro Orro1, John Hatton1, Matteo Gnocchi1, Andrea Manconi1 and Luciano Milanesi1*
Bioinformatics molecular dynamics and docking pipeline analysis for high-throughput genome analysis and drug discovery oriented to personalized pain therapy in non-responsive patients.
(2013) Front. Neuroinform. Conference, Stockholm, Sweden, 27-29 agosto 2013
Cichero E, Ligresti A, Allarà M, di Marzo V, Lazzati Z, D'Ursi P, Marabotti A, Milanesi L, Spallarossa A, Ranise A, Fossa P.
Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor
(2011) in European journal of medicinal chemistry
Lazzati, Zelda; D'Ursi, Pasqualina; Orro, Alessandro; Bolzacchini, Ezio; Milanesi, Luciano
Nuclear Receptors Database for predictive toxicity of EDC
(2010) in Journal of biotechnology
Bolzacchini E., Ferrero L., Perrone M.G., Lazzati Z., DUrsi P., Orro A., Gnocchi M., Moscatelli M., Milanesi L.
Piattaforma bioinformatica per lo studio della relazione tra particolato atmosferico e salute umana.
(2010) Quarto Convegno Nazionale sul Particolato Atmosferico
Lazzati Z., D'Ursi P., Orro A., Bolzacchini E., Ferrero L., Sangiorgi G., Perrone M.G., Gnocchi M., Milanesi L.
Analisi in Silico dei Meccanismi dAzione (MOA) correlati allesposizione da Particolato Atmosferico: esame critico del caso del Bisfenolo A.
(2010) Quarto Convegno Nazionale sul Particolato Atmosferico
Lazzati Z., DUrsi P., Orro A., Moscatelli M., Santoro S., Bolzacchini E., Milanesi L.
Realizzazione di una banca dati strutturale dei recettori nucleari umani per la predizione della tossicità dei distruttori endocrini.
(2010) 83° Convegno Nazionale della Società Italiana di Biologia Sperimentale (SIBS)
Moscatelli M., Bolzacchini E., D'Ursi P., Ferrero L., Gnocchi M., Lazzati Z., Orro A., Perrone M.G., Milanesi L.
Bioinformatics infrastructure for the analysis of the relationships between particulate matter and human health.
(2010) BITS2010
Lazzati Z., D'Ursi P., Orro A., Bolzacchini E., Milanesi L.
Nuclear receptors database for predictive toxicity of EDC.
(2010) 14th International Biotechnology Symposium and Exhibition
DUrsi P., Lazzati Z., Bolzacchini E., Milanesi L.
Reverse Molecular Docking for the identification of protein targets and pathways of endocrine disruptor Bisphenol A.
(2010) International Council of Chemical Associations Long-Range Research Initiative (ICCA-LRI) & JRC workshop, Integrating New Advances in Exposure Science and Toxicity Testing: Next Steps.
D'Ursi P; Chiappori F; Merelli I; Cozzi P; Rovida E; Milanesi L
Virtual screening pipeline and ligand modelling for H5N1 neuraminidase
(2009) in Biochemical and biophysical research communications (Print)
Chiappori F; D'Ursi P; Merelli I; Milanesi L; Rovida E
In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study
(2009) in BMC bioinformatics
Lazzati Z., DUrsi P., Rovida E., Gambaro A., Zangrando R., Chiappori F., Milanesi L., Bolzacchini E.
A Docking Procedure for the identification of potential Bisphenol A protein targhets and characterization of the major environmental matrix involved in their pathways
(2009) XXIII Congresso Nazionale della Società Chimica Italiana
D'Ursi P., Lazzati Z., Bolzacchini E., Milanesi L.
Reverse molecular docking and pathway analysis for the identification of protein targets and pathways of endocrine disruptor Bisphenol A
(2009) Sysbiohealth Simposium
Milanesi, Luciano; Alfieri, Roberta; Mosca, Ettore; Viti, Federica; D'Ursi, Pasqualina; Merelli, Ivan
Sys-bio gateway: A framework of bioinformatics database resources oriented to systems biology
(2009) in International Workshop on Portals for Life Sciences, 2009
Corrada Dario, Pasqualina DUrsi, Sara Botti, Aldo Luperini, Luciano Milanesi,Ermanna Rovida
3D-Structure Prediction of the Modular Protein Sialoadhesin Using a Multi-step Modelling Strategy
(2008) SysBioHealth 2008 , 24th to 25th November, Bologna Italy, Bologna, Italy, 18-20/03/2009
D'Ursi P, Marino F, Caprera A, Milanesi L, Faioni EM, Rovida E.
ProCMD: a database and 3D web resource for protein C mutants.
(2007) in BMC bioinformatics
Rovida E; Merati G; D'Ursi P; Zanardelli S; Marino F; Fontana G; Castaman G; Faioni EM
Identification and computationally-based structural interpretation of naturally occurring variants of human protein C.
(2007) in Human mutation
Ermanna Rovida 1, Giuliana Merati 2, Pasqualina D'Ursi 3, Sara Zanardelli 2, Francesca Marino 1, Gessica Fontana 4, GiancarloCastaman 5, Elena M. Faioni 4
Identification and computionally-based structural interpretation of naturally occuring variants of human protein C
(2007) in Human mutation
DUrsi P. Chiappori F., Salvi E., Merelli I., Rovida E., Milanesi L
Grid docking simulation for comparative ligand binding of Neurominidase structures
(2007) BITS2007, Napoli
DUrsi P., Marino F., Caprera A., Milanesi L., Faioni E., Rovida E.
3D-protein C mutation database: integration of structural, functional and clinical data of natural protein C mutants
(2006) BITS2006, Bologna, Italy
Marino F., Morra G., DUrsi P., Salvi E., Milanesi L., Faioni E., Rovida E.
Molecular dynamics and docking of the G216D mutation in the catalytic domain of activated protein C.
(2006) BITS2006, Bologna, Italy
Rovida E., DUrsi P., Morra G., Marino F., Milanesi L.,Merati G.,Faioni E
Structural interpretation of the G216D mutation in the catalytic domain of activated protein C by computational approach
(2005) 6th European Symposium of the Protein Society, Barcellona Spain
Rovida E., DUrsi P., Marino F., Caprera A., , Milanesi L., Merati G.,Faioni E
3D-protein C mutation database: integration of structural, functional and clinical data of natural Protein C mutants
(2005) ISMB 2005, Michigan, USA
DUrsi P., Rovida E., Merati G., Biguzzi E., Caprera A., Milanesi L., Faioni E.
Computational analysis of naturally occurring protein C mutants: electrostatic properties implications.
(2004) Bioinformatics Italian Society Meeting (BITS 2004), Padova
Tagliavini, F; Forloni, G; D'Ursi, P; Bugiani, O; Salmona, M
Studies on peptide fragments of prion proteins
(2001) in Advances in protein chemistry and structural biology (Online)
