Clarissa Consolandi

The information published in this page are entirely managed by CLARISSA CONSOLANDI who is completely responsible for it.

She has accumulated a great experience in molecular biology and biotechnology, focusing her attention especially on microarray platforms, NGS and Single-cell Sequencing in the field of Genomics, Trascriptomics and Metagenomics. He is involeved in: - Single-cell sequencing activity by 10X Genomics platform for the characterization of the molecular states of individual cells through their transcriptional profiles. This approach, differently from the in "bulk" RNA-seq, allows studying cell-to-cell variability in terms of transcriptomic dynamics and cellular heterogeneity. - Ultra-massive sequencing activity, by Illumina and Roche platforms, of °metagenomes [Human Microbiome (Gut, Oral, Nasal, Vaginal and Rectal Microbiome); Animal Microbiome (GM studies in model mice; GM exploration in bottlenose dolphins as peculiar GM-host configuration); Environmental Microbiome (water safety assessment tools, soil crusts) °eukaryotic and prokaryotic transcriptomes °entire prokaryotic genomes °particular regions of interest in human genomes in relation to diseases Good communication skills are gained during didactic and academic activities in participation of National and International Congresses, in organization of National Congresses, during lessons to students from Universities and PhD Schools.
Organizational, managerial skills and independent management capacities are acquired as Coordinator and Member of Unit in different Projects financed by Italian Ministry of University and Research, European Community, Cariplo foundation and Regione Lombardia with great capacity to work in team, in the preparation of technical reports and reports to describe the progress of the works or to contribute to the allocation of funds for national and / or international projects of Research and in writing of scientific manuscripts on the basis of the experimental data obtained.

Interest areas:

Omics technologies: Genomics, Trascriptomics, Metagenomics applied in different fields (human diseases; study of microorganisms)


Contacts

Phone: 0226422764
Skype: clarissa.consolandi

International Ids


H-indexes

Google Scholar H-Index: 31
Scopus H-Index: 26
ISI-WoS H-Index: 23

Experience

Permanent position as full-time Researcher III professional Level
Company: ITB - Istituto di tecnologie biomediche
Time period: 02/2004 - today
  • Single-cell sequencing activity by 10X Genomics platform for the characterization of the molecular states of individual cells through their transcriptional profiles. This approach, differently from the in "bulk" RNA-seq, allows studying cell-to-cell variability in terms of transcriptomic dynamics and cellular heterogeneity.
  • Ultra-massive sequencing activity, by Illumina and Roche platforms, of °metagenomes [Human Microbiome (Gut, Oral, Nasal, Vaginal and Rectal Microbiome); Animal Microbiome (GM studies in model mice; GM exploration in bottlenose dolphins as peculiar GM-host configuration); Environmental Microbiome (water safety assessment tools, soil crusts) °eukaryotic and prokaryotic transcriptomes °entire prokaryotic genomes °particular regions of interest in human genomes in relation to diseases


Education

Dottorato di Ricerca in Medicina Molecolare
Università degli Studi di Milano - via F.lli Cervi 93 Segrate (Mi)
Graduation date: 2004-01-16
Thesis: "Development of DNA Microarrays for human single nucleotide polymorphisms detection"

Laurea in Scienze Biologiche
Università degli Studi di Milano - via Celoria Milano
Graduation date: 2000-07-21
Thesis: Sviluppo della Tecnologia dei DNA Microarrays per lo studio di mutazioni e l'identificazione di polimorfismi


Languages

Production Understanding
Written Oral Written Oral Notes
English - Professional working proficiencyB2B1B2B1

Training period of two months at the Molecular Medicine Group of the Research Department of Uppsala University Hospital (Uppsala, Sweden), under supervision of Prof. Ann-Christine Syvänen, with the Project "Minisequencing-primer extension technology applied to a tag-array format".


Research activities classification (ERC)

GENETICS, GENOMICS, BIOINFORMATICS AND SYSTEMS BIOLOGY: GENETICS, POPULATION GENETICS, MOLECULAR GENETICS, GENOMICS, TRANSCRIPTOMICS, PROTEOMICS, METABOLOMICS, BIOINFORMATICS, COMPUTATIONAL BIOLOGY, BIOSTATISTICS, BIOLOGICAL MODELLING AND SIMULATION, SYSTEMS BIOLOGY, GENETIC EPIDEMIOLOGY
LIFE SCIENCES

Skills

GENOMICS
HUMAN DISEASES
METAGENOMICS
MICROBIOME
TRASCRIPTOMICS

Research products

Andrea Baragetti , Marco Severgnini , Elena Olmastroni , Carola Conca Dioguardi , Elisa Mattavelli , Andrea Angius , Luca Rotta , Javier Cibella , Giada Caredda , Clarissa Consolandi , Liliana Grigore , Fabio Pellegatta , Flavio Giavarini , Donatella Caruso , Giuseppe Danilo Norata , Alberico Luigi Catapano and Clelia Peano

Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis

Andrea Baragetti , Marco Severgnini , Elena Olmastroni , Carola Conca Dioguardi , Elisa Mattavelli , Andrea Angius , Luca Rotta , Javier Cibella , Giada Caredda , Clarissa Consolandi , Liliana Grigore , Fabio Pellegatta , Flavio Giavarini , Donatella Caruso , Giuseppe Danilo Norata , Alberico Luigi Catapano (2021) in Nutrients
Spreafico M.; Mangano E.; Mazzola M.; Consolandi C.; Bordoni R.; Battaglia C.; Bicciato S.; Marozzi A.; Pistocchi A.

The Genome-wide impact of Nipblb loss-of-function on Zebrafish gene expression

(2020) in International journal of molecular sciences (Print)
van der Houwen, Tim B.; van Laar, Jan A. M.; Kappen, Jasper H.; van Hagen, Petrus M.; de Zoete, Marcel R.; van Muijlwijk, Guus H.; Berbers, Roos-Marijn; Fluit, Ad C.; Rogers, Malbert; Groot, James; Hazelbag, C. Marijn; Consolandi, Clarissa; Severgnini, Marco; Peano, Clelia; D'Elios, Mario M.; Emmi, Giacomo; Leavis, Helen L.

Behcet's Disease Under Microbiotic Surveillance? A Combined Analysis of Two Cohorts of Behcet's Disease Patients

(2020) in Frontiers in immunology
Lopetuso, Loris Riccardo; Severgnini, Marco; Pecere, Silvia; Ponziani, Francesca Romana; Boskoski, Ivo; Larghi, Alberto; Quaranta, Gianluca; Masucci, Luca; Ianiro, Gianluca; Camboni, Tania; Gasbarrini, Antonio; Costamagna, Guido; Consolandi, Clarissa; Cammarota, Giovanni

Esophageal microbiome signature in patients with Barrett's esophagus and esophageal adenocarcinoma

(2020) in PloS one
Marangoni A, Ceccarani C, Camboni T, Consolandi C, Foschi C, Salvo M, Gaspari V, D'Antuono A, Belletti M, Re MC, Severgnini M.

Pharyngeal microbiome alterations during Neisseria gonorrhoeae infection

(2020) in PloS one
Ianiro G.; Rossi E.; Thomas A.M.; Schinzari G.; Masucci L.; Quaranta G.; Settanni C.R.; Lopetuso L.R.; Armanini F.; Blanco-Miguez A.; Asnicar F.; Consolandi C.; Iacovelli R.; Sanguinetti M.; Tortora G.; Gasbarrini A.; Segata N.; Cammarota G.

Faecal microbiota transplantation for the treatment of diarrhoea induced by tyrosine-kinase inhibitors in patients with metastatic renal cell carcinoma

(2020) in Nature communications
Verrillo, Lucia and Mangano, Eleonora and Drongitis, Denise and Merelli, Ivan and Pischedda, Francesca and Piccoli, Giovanni and Consolandi, Clarissa and Bordoni, Roberta and Miano, Maria Giuseppina

A reliable strategy for single-cell RNA sequencing analysis using cryoconserved primary cortical cells.

(2020) in Journal of neuroscience methods
Ceccarani, Camilla; Foschi, Claudio; Parolin, Carola; D'Antuono, Antonietta; Gaspari, Valeria; Consolandi, Clarissa; Laghi, Luca; Camboni, Tania; Vitali, Beatrice; Severgnini, Marco; Marangoni, Antonella

Diversity of vaginal microbiome and metabolome during genital infections

(2019) in Scientific reports (Nature Publishing Group)
Ceccarani, Camilla; Marangoni, Antonella; Severgnini, Marco; Camboni, Tania; Laghi, Luca; Gaspari, Valeria; D'Antuono, Antonietta; Foschi, Claudio; Re, Maria Carla; Consolandi, Clarissa

Rectal Microbiota Associated With Chlamydia trachomatis and Neisseria gonorrhoeae Infections in Men Having Sex With Other Men

(2019) in Frontiers in cellular and infection microbiology
Barichella M1, Severgnini M2, Cilia R1, Cassani E1, Bolliri C1, Caronni S1, Ferri V1, Cancello R3, Ceccarani C2,4, Faierman S1, Pinelli G1,5, De Bellis G2, Zecca L2,6, Cereda E7, Consolandi C2, Pezzoli G1.

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

(2019) in Movement disorders
Visualize all the publications (since 2016)